Bipolar radiofrequency ablation using internally cooled electrodes in ex vivo bovine liver: prediction of coagulation volume from applied energy

Invest Radiol. 2007 Jan;42(1):29-36. doi: 10.1097/01.rli.0000248973.95949.eb.

Abstract

Objective: We sought to evaluate the relationship between parameters of bipolar radiofrequency (RF) ablation using internally cooled electrodes.

Materials and methods: Bipolar RF ablations (n = 24) were performed in ex vivo bovine liver using an internally cooled applicator with 2 electrodes located on the same shaft. The power-output was systematically varied (20-75 W). On the basis of our experimental data, mathematical functions were fitted and the goodness-of-fit was assessed by the parameter R.

Results: The duration to induce an increase of tissue resistance and the amount of applied energy increased with a decreased power-output. The maximum short-axis was 4.5 cm (20 W) and required an application of 64 kilojoules (kJ). The volume of coagulation can be determined as a function of the duration of energy application (R = 0.954) and the amount of applied energy (R = 0.945).

Conclusion: The amount of applied energy and the duration of energy application can predict the volume of induced coagulation and may be useful to control internally cooled bipolar RF ablation.

MeSH terms

  • Animals
  • Catheter Ablation / instrumentation*
  • Catheter Ablation / methods
  • Cattle
  • Cold Temperature*
  • Electrodes*
  • In Vitro Techniques
  • Liver / surgery*
  • Models, Statistical