Complete 1H and 13C NMR assignments of sesquiterpene glucosides from Ixeris sonchifolia

Magn Reson Chem. 2007 Mar;45(3):275-8. doi: 10.1002/mrc.1953.

Abstract

Four sesquiterpene glucosides were isolated from Ixeris sonchifolia Hance. The structure of a new compound (1) was assigned as 9beta-monohydroxy-2,12-dioxo-guaia-3,11(13)-dien-1alpha,5alpha,6beta,7alpha,9beta,10alphaH-12,6-olide-9-O-beta-D- glucopyranoside (ixerinoside). In addition, unambiguous and complete assignments of (1)H NMR chemical shifts for crepidiaside A (2), ixerin Z (3), and 11,13alpha-dihydroixerin Z (4) are presented. The assignments were achieved by two-dimensional NMR (gCOSY, gHSQC, gHMBC, NOESY) and one-dimensional nuclear Overhauser effect (NOE) experiments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asteraceae / chemistry*
  • Carbon Isotopes
  • Glucosides / chemistry*
  • Glucosides / isolation & purification
  • Magnetic Resonance Spectroscopy / methods*
  • Magnetic Resonance Spectroscopy / standards*
  • Molecular Conformation
  • Protons
  • Reference Standards
  • Sensitivity and Specificity
  • Sesquiterpenes / chemistry*
  • Sesquiterpenes / isolation & purification
  • Stereoisomerism

Substances

  • 11,13-dihydroixerin Z
  • 9-monohydroxy-2,12-dioxoguaia-3,11(13)-dien-1,5,6,7,9,10H-12,6-olide-9-O-glucopyranoside
  • Carbon Isotopes
  • Glucosides
  • Protons
  • Sesquiterpenes