Informatics can be understood as an element of management, dealing with structures of files, algorithms and hardware. The most important prerequisite to successful use of informatics is an optimal compatibility between these single elements. To realize this compatibility and to ascertain a permanent operability of informatics in pathology, the realization of the following two conditions are advisable: 1) The differentiation between a general administrative system of the whole department of pathology and systems of special units (e.g. laboratories); 2) the modularity of the laboratory systems.