Assessment of in vivo 5-lipoxygenase activity by analysis of leukotriene B4 in saliva: effects of treatment with zileuton

J Allergy Clin Immunol. 2007 May;119(5):1267-8. doi: 10.1016/j.jaci.2006.12.650. Epub 2007 Jan 25.
No abstract available

Publication types

  • Clinical Trial
  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Arachidonate 5-Lipoxygenase / drug effects
  • Arachidonate 5-Lipoxygenase / metabolism*
  • Chromatography, High Pressure Liquid
  • Double-Blind Method
  • Evaluation Studies as Topic
  • Female
  • Flow Cytometry
  • Humans
  • Hydroxyurea / analogs & derivatives*
  • Hydroxyurea / pharmacology
  • Leukocytes, Mononuclear / drug effects
  • Leukocytes, Mononuclear / metabolism
  • Leukotriene Antagonists / pharmacology*
  • Leukotriene B4 / analysis*
  • Male
  • Middle Aged
  • Saliva / chemistry*

Substances

  • Leukotriene Antagonists
  • Leukotriene B4
  • Arachidonate 5-Lipoxygenase
  • zileuton
  • Hydroxyurea