Short-term intraocular pressure trends after intravitreal triamcinolone injection

Am J Ophthalmol. 2007 Feb;143(2):365-7. doi: 10.1016/j.ajo.2006.08.033. Epub 2006 Sep 28.

Abstract

Purpose: To report the trends in intraocular pressures (IOP) within the first week after intravitreal injection of triamcinolone acetonide (Kenalog) for the treatment of retinal disease.

Design: Retrospective chart review.

Methods: Review of 43 consecutive patients and 50 intravitreal injections of 4 mg triamcinolone acetonide. Analysis of the effect on IOP was performed.

Results: The mean preinjection IOP was 14.60 +/- 3.71 mm Hg (mean +/- SD) (range, 9 to 26 mm Hg). The mean postinjection IOP (30 minutes after injection) was 19.64 +/- 7.43 mm Hg (range, 5 to 45 mm Hg). Mean IOP change before and after injection was 4.83 +/- 7.10 mm Hg. The mean IOP one to two days after injection was 15.32 +/- 4.41. mm Hg (range, 6 to 27 mm Hg). The mean IOP five to seven days after injection was 15.94 +/- 4.86 mm Hg (range, 5 to 28 mm Hg).

Conclusions: Intravitreal triamcinolone acetonide injection in this limited series does not cause a marked increase in IOP within the first week after the procedure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Glucocorticoids / administration & dosage*
  • Humans
  • Injections
  • Intraocular Pressure / drug effects*
  • Retrospective Studies
  • Tonometry, Ocular
  • Triamcinolone Acetonide / administration & dosage*
  • Vitreous Body

Substances

  • Glucocorticoids
  • Triamcinolone Acetonide