Tn1403, a multiple-antibiotic resistance transposon made up of three distinct transposons

H W Stokes; Liam D H Elbourne; Ruth M Hall

doi:10.1128/AAC.01279-06

Tn1403, a multiple-antibiotic resistance transposon made up of three distinct transposons

Antimicrob Agents Chemother. 2007 May;51(5):1827-9. doi: 10.1128/AAC.01279-06. Epub 2007 Jan 29.

Authors

H W Stokes¹, Liam D H Elbourne, Ruth M Hall

Affiliation

¹ School of Molecular and Microbial Biosciences, Biochemistry and Microbiology Building G08, The University of Sydney, NSW, Australia.

Abstract

Transposon Tn1403 from a clinical Pseudomonas strain is composed of three transposons, including Tn5393c. A related transposon Tn1404* from a plant-associated Pseudomonas strain lacks Tn5393 but includes a transposon carrying the tet(C) tetracycline resistance determinant. These compound transposons illustrate the role of preexisting transposons in generating clusters of antibiotic resistance genes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
DNA Transposable Elements*
Drug Resistance, Multiple, Bacterial / genetics*
Molecular Sequence Data
Pseudomonas aeruginosa / genetics*

Substances

DNA Transposable Elements

Associated data

GENBANK/AF313472