Abstract
The immunogenic iron-regulated FetA outer membrane protein of Neisseria meningitidis is one of various outer membrane proteins that have been considered potential meningococcal vaccine candidates. In this report, we describe the characterization of three meningococcal isolates that have deleted fetA sequences through genetic recombination at repetitive elements.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Bacterial Outer Membrane Proteins / genetics*
-
Base Sequence
-
DNA, Bacterial / chemistry
-
DNA, Bacterial / genetics
-
Genes, Bacterial*
-
Humans
-
Meningococcal Infections / microbiology
-
Molecular Sequence Data
-
Neisseria meningitidis, Serogroup B / genetics*
-
Neisseria meningitidis, Serogroup B / isolation & purification
-
Neisseria meningitidis, Serogroup C / genetics*
-
Neisseria meningitidis, Serogroup C / isolation & purification
-
Recombination, Genetic
-
Repetitive Sequences, Nucleic Acid / genetics
-
Sequence Deletion
Substances
-
Bacterial Outer Membrane Proteins
-
DNA, Bacterial
-
FrpB protein, bacteria
Associated data
-
GENBANK/EF153762
-
GENBANK/EF153763
-
GENBANK/EF153764
-
GENBANK/EF153765