Can immunity induced by the human influenza virus N1 neuraminidase provide some protection from avian influenza H5N1 viruses?

Laura Gillim-Ross; Kanta Subbarao

doi:10.1371/journal.pmed.0040091

Can immunity induced by the human influenza virus N1 neuraminidase provide some protection from avian influenza H5N1 viruses?

PLoS Med. 2007 Feb;4(2):e91. doi: 10.1371/journal.pmed.0040091.

Authors

Laura Gillim-Ross¹, Kanta Subbarao

Affiliation

¹ Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

Abstract

Gillim-Ross and Subbarao discuss a new study inPLoS Medicine that suggests that immunity to the human influenza virus N1 NA cross-reacts with the avian N1 NA, and that this cross-reactivity may be sufficient to protect against infection with avian influenza virus H5N1.

Publication types

Review

MeSH terms

Antibodies, Viral / immunology*
Humans
Immunity / immunology*
Influenza A Virus, H3N2 Subtype / enzymology
Influenza A Virus, H3N2 Subtype / immunology*
Influenza A Virus, H5N1 Subtype / pathogenicity*
Influenza Vaccines / therapeutic use*
Influenza, Human / prevention & control*
Influenza, Human / virology
Neuraminidase / immunology*
Prognosis

Substances

Antibodies, Viral
Influenza Vaccines
Neuraminidase