The role of pre-operative CT-guided FNAB for parapharyngeal space tumors

Otolaryngol Head Neck Surg. 2007 Mar;136(3):411-4. doi: 10.1016/j.otohns.2006.10.006.

Abstract

Objective: To determine the role of computed tomography (CT)-guided fine needle aspiration biopsy (FNAB) in surgical planning for parapharyngeal space (PPS) tumors.

Design and setting: Chart review of 49 consecutive patients with surgically treated PPS tumors from 1995 to 2005.

Results: Twenty-nine patients had CT-guided FNAB. A cytopathologic diagnosis that was the same as final pathology was rendered in 14 (48%) patients; suggestive but not conclusive in 6 (21%) patients; discordant in 3 (10%) patients; and 6 (21%) patients had a nondiagnostic result. Fourteen of 15 patients who had a final histopathologic finding of pleomorphic adenoma had a correct or highly suggestive preoperative FNAB diagnosis. The positive predictive value for CT-guided FNAB to identify benign tumors is 90%, (18 of 20) but to identify malignant PPS tumors is 75% (3 of 4).

Conclusion: CT-guided FNAB of PPS tumors is helpful to predict the nature of the PPS tumors (especially benign), which allows the surgeon and patient to plan for treatment, accordingly.

MeSH terms

  • Adenocarcinoma / pathology
  • Adenocarcinoma / surgery
  • Adenoma, Pleomorphic / pathology
  • Adenoma, Pleomorphic / surgery
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Fine-Needle / methods*
  • Cytodiagnosis
  • Diagnosis, Differential
  • Female
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / surgery
  • Humans
  • Male
  • Middle Aged
  • Patient Care Planning
  • Pharyngeal Neoplasms / pathology*
  • Pharyngeal Neoplasms / surgery
  • Predictive Value of Tests
  • Preoperative Care
  • Radiography, Interventional*
  • Retrospective Studies
  • Tomography, X-Ray Computed*