Extensive exfoliative dermatitis induced by non-ionic contrast medium Iodixanol (Visipaque) used during percutaneous coronary intervention

Int J Cardiol. 2008 Feb 29;124(2):e25-7. doi: 10.1016/j.ijcard.2006.11.179. Epub 2007 Mar 2.

Abstract

We report a case of extensive exfoliative dermatitis in a patient appearing 3 days after intracoronary administration of non-ionic contrast medium Iodixanol (Visipaque) during the primary percutaneous coronary intervention. The patient presented with acute myocardial infarction and has never exposed to any X-ray contrast medium. The patient was successfully treated with corticosteroid, antihistamines and antibiotics for the prevention of secondary bacterial infection. The patient was recovered 8 days after the anti-allergic medical management. This case can be a rare example of late-onset allergic reaction to a non-ionic contrast medium Iodixanol presented with extensive exfoliative dermatitis.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Angioplasty, Balloon, Coronary / adverse effects
  • Angioplasty, Balloon, Coronary / methods*
  • Chest Pain / diagnosis
  • Chest Pain / etiology
  • Contrast Media / adverse effects*
  • Coronary Angiography
  • Dermatitis, Exfoliative / chemically induced*
  • Dermatitis, Exfoliative / drug therapy
  • Dermatitis, Exfoliative / physiopathology
  • Drug-Eluting Stents
  • Emergency Service, Hospital
  • Follow-Up Studies
  • Histamine H1 Antagonists / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / therapy*
  • Risk Assessment
  • Severity of Illness Index
  • Steroids / therapeutic use
  • Triiodobenzoic Acids / adverse effects*

Substances

  • Contrast Media
  • Histamine H1 Antagonists
  • Steroids
  • Triiodobenzoic Acids
  • iodixanol