Assignment of the gene encoding DNA ligase I to human chromosome 19q13.2-13.3

Genomics. 1992 Jan;12(1):164-6. doi: 10.1016/0888-7543(92)90422-o.

Abstract

The gene encoding DNA ligase I has been mapped on human chromosome 19 by analysis of rodent-human somatic cell hybrids informative for this chromosome and by two-color fluorescence in situ hybridization. The DNA ligase I gene (LIG1) is localized to 19q13.2-13.3 and is distal to ERCC1, the most telomeric of three DNA repair genes on this chromosome.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Blotting, Southern
  • Chromosome Banding
  • Chromosome Mapping
  • Chromosomes, Human, Pair 19*
  • DNA Ligase ATP
  • DNA Ligases / genetics*
  • Humans
  • Hybrid Cells
  • Microscopy, Fluorescence
  • Nucleic Acid Hybridization

Substances

  • LIG1 protein, human
  • DNA Ligases
  • DNA Ligase ATP