Abstract
A combination of biochemistry in animal cell-free systems and genetics in yeast is revealing the molecular machinery of the secretory pathway of eukaryotes. Transporting vesicles have a simple coat structure and employ a general mechanism for fusion that is conserved in evolution.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Amino Acid Sequence
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Animals
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Cell Physiological Phenomena*
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Endoplasmic Reticulum / physiology*
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Golgi Apparatus / physiology*
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Intracellular Membranes / physiology
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Membrane Fusion
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Models, Biological
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Molecular Sequence Data
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Saccharomyces cerevisiae / physiology
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Signal Transduction