[Immunohistochemistry and surgical approaches in solitary fibrous tumor of the pleura]

Cir Esp. 2007 Mar;81(3):155-8. doi: 10.1016/s0009-739x(07)71289-7.
[Article in Spanish]

Abstract

Solitary fibrous tumor of the pleura (SFTP) is a rare, benign, slow-growing neoplasm that arises from the submesothelial cells of the pleura. Usually, resection of the tumor and adjacent structures are sufficient for resolution. Nowadays, videothoracoscopy (VTC) allows adequate access for the surgical treatment of these tumors. CD34 antigen positivity is a differential feature with mesothelioma. We present our experience with 15 patients with SFTP (nine women and six men) who underwent surgical resection in the last 12 years (10 thoracotomies, one sternotomy and four VTC). Only four patients were symptomatic at diagnosis. In our opinion, VTC is a less invasive diagnostic and therapeutic approach than thoracotomy that provides an adequate approach for the resection of SFTP in selected patients. Because of the malignant potential of this tumor, long-term follow-up is mandatory.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Antigens, CD34 / immunology
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry
  • Male
  • Mesothelioma / immunology
  • Mesothelioma / pathology
  • Mesothelioma / surgery
  • Middle Aged
  • Neoplasms, Fibrous Tissue / immunology*
  • Neoplasms, Fibrous Tissue / pathology
  • Neoplasms, Fibrous Tissue / surgery*
  • Pleural Neoplasms / immunology*
  • Pleural Neoplasms / pathology
  • Pleural Neoplasms / surgery*
  • Thoracic Surgery, Video-Assisted / instrumentation*
  • Thoracic Surgery, Video-Assisted / methods

Substances

  • Antigens, CD34