Abstract
An ethyl acetate extract of bark from Evodia elleryana produced significant growth inhibition of Mycobacterium tuberculosis at concentrations only minimally inhibitory to human T cells. The crude extract yielded 95% inhibition of TB at 50 microg/ml. The crude extract yielded 29% growth inhibition of human T-cells in culture at that concentration.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Antitubercular Agents / administration & dosage
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Antitubercular Agents / pharmacology*
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Antitubercular Agents / therapeutic use
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Dose-Response Relationship, Drug
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Evodia*
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Humans
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Microbial Sensitivity Tests
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Mycobacterium tuberculosis / drug effects*
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Phytotherapy*
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Plant Bark
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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T-Lymphocytes / drug effects
Substances
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Antitubercular Agents
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Plant Extracts