Neutrophilic dermatosis of the hands: presentation of eight cases and review of the literature

J Dermatol. 2007 Apr;34(4):243-7. doi: 10.1111/j.1346-8138.2007.00261.x.

Abstract

Pustular dermatosis of the dorsal hands is a peculiar variant of Sweet's syndrome described by Strutton et al. Nevertheless, not all authors accept this entity. We present a retrospective study of eight cases of neutrophilic vasculitis of the hands. Three patients presented with lesions only on the dorsal hands, three with lesions on the palmar surface and two with lesions on the dorsal and palmar surfaces of the hands. The patients with lesions on the dorsal surface presented a pustular aspect, and the histopathological examination revealed a high degree of vascular damage with presence of vasculitis and, in one case, with fibrinoid necrosis. Therefore, the term pustular vasculitis of the dorsal hands introduced by Strutton et al. should probably be conserved. Our cases may have demonstrated a peculiar clinicopathological disease with its own entity.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Female
  • Hand Dermatoses / drug therapy
  • Hand Dermatoses / pathology*
  • Humans
  • Male
  • Middle Aged
  • Neutrophils