[Histological charakteristics of tongue and floor of the mouth neoplasms and their clinical prognostic value]

Otolaryngol Pol. 2006;60(6):823-7.
[Article in Polish]

Abstract

Introduction: The number of histological classifications has been introduced to asses the squamous cell carcinoma in head and neck. The Jakobsson histological system employs 8 different morphological characteristics. Four of them concerning tumor cell population and another four describe relation to the adjacent tissues.

Material and methods: The material comprised tissue specimens from 80 patients with squamous cell carcinoma of the tongue and floor of the mouth who underwent the primary surgery. All the data concerning Jakobsson classification, histological differentiation G, TNM classification, and recurrence and survival rates were recorded and analyzed.

Results: Any significant correlation has been found between Jakobsson classification and histological differentiation. Nevertheless statistically significant correlation between Jakobsson classification and T of the tumor, nodal metastases and local and nodal relapse has been recorded.

Conclusions: The Jakobsson classification constitute the important supplement of the routine histological assessment and may significantly contribute to the choice of therapy.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Squamous Cell / classification
  • Carcinoma, Squamous Cell / pathology*
  • Carcinoma, Squamous Cell / surgery*
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mouth Floor*
  • Mouth Neoplasms / classification
  • Mouth Neoplasms / pathology*
  • Mouth Neoplasms / surgery*
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery
  • Neoplasm Staging / methods
  • Prognosis
  • Tongue Neoplasms / classification
  • Tongue Neoplasms / pathology*
  • Treatment Outcome