The mass of the Sindbis virus nucleocapsid suggests it has T = 4 icosahedral symmetry

Virology. 1992 Mar;187(1):329-32. doi: 10.1016/0042-6822(92)90322-g.

Abstract

The mass of the nucleocapsid of the alphavirus Sindbis was determined by scanning transmission electron microscopy. The nucleocapsid was found to have an average mass of 10.54 x 10(6) Da with the largest percentage of particles showing a mass of 10.7 to 10.9 x 10(6) Da. These data predict that the nucleocapsid contains 240 copies of protein and is a T = 4 icosahedron.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Capsid / chemistry*
  • Capsid / ultrastructure
  • Macromolecular Substances
  • Microscopy, Electron
  • Sindbis Virus / chemistry*
  • Sindbis Virus / ultrastructure
  • Viral Proteins / chemistry
  • Viral Proteins / ultrastructure

Substances

  • Macromolecular Substances
  • Viral Proteins