Neurofibromatosis 1, and Not TP53, seems to be the main target of chromosome 17 deletions in de novo acute myeloid leukemia

J Clin Oncol. 2007 Mar 20;25(9):1151-2; author reply 1152-3. doi: 10.1200/JCO.2006.09.3013.
No abstract available

Publication types

  • Comment
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Chromosomes, Human, Pair 17*
  • Gene Deletion*
  • Gene Expression Profiling
  • Gene Expression Regulation, Leukemic*
  • Humans
  • In Situ Hybridization, Fluorescence
  • Leukemia, Myeloid / genetics*
  • Loss of Heterozygosity
  • Neurofibromatosis 1 / genetics*
  • Oligonucleotide Array Sequence Analysis
  • Reproducibility of Results
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • TP53 protein, human
  • Tumor Suppressor Protein p53