Abstract
We found 31 different emm-toxin genotypes among 74 group A streptococcal isolates causing invasive infections in French children. The predominant emm types were emm1 (25%), emm3 (8%), emm4 (8%), emm6 (7%), and emm89 (9%). Sixteen percent of isolates harbored the streptococcal invasive locus, half of them belonging to emm4.
MeSH terms
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Adolescent
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Antigens, Bacterial / classification
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Antigens, Bacterial / genetics
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Bacterial Outer Membrane Proteins / classification
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Bacterial Outer Membrane Proteins / genetics
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Bacterial Proteins / genetics*
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Carrier Proteins / classification
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Carrier Proteins / genetics
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Child
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Child, Preschool
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DNA, Bacterial / analysis
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DNA, Bacterial / genetics
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DNA, Bacterial / isolation & purification
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France / epidemiology
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Humans
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Infant
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Molecular Epidemiology*
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Polymerase Chain Reaction
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Streptococcal Infections / epidemiology*
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Streptococcal Infections / microbiology
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Streptococcus pyogenes / classification
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Streptococcus pyogenes / genetics*
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Streptococcus pyogenes / pathogenicity*
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Virulence
Substances
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Antigens, Bacterial
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Bacterial Outer Membrane Proteins
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Bacterial Proteins
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Carrier Proteins
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DNA, Bacterial
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streptococcal M protein