Activity of faropenem against middle ear fluid pathogens from children with acute otitis media in Costa Rica and Israel

Antimicrob Agents Chemother. 2007 Jun;51(6):2230-5. doi: 10.1128/AAC.00049-07. Epub 2007 Mar 26.

Abstract

Faropenem was tested against 1,188 middle ear fluid pathogens from children in Israel and Costa Rica. Against Streptococcus pneumoniae and Haemophilus influenzae, faropenem was the most active beta-lactam, with activity that was similar to or greater than of the other oral antimicrobial classes studied. Faropenem was also active against Moraxella catarrhalis and Streptococcus pyogenes.

MeSH terms

  • Acute Disease
  • Anti-Bacterial Agents / pharmacology*
  • Child
  • Costa Rica
  • Ear, Middle / microbiology*
  • Haemophilus influenzae / drug effects*
  • Humans
  • Israel
  • Microbial Sensitivity Tests / methods
  • Moraxella catarrhalis / drug effects
  • Otitis Media with Effusion / microbiology*
  • Streptococcus pneumoniae / drug effects*
  • Streptococcus pyogenes / drug effects
  • beta-Lactams / pharmacology*

Substances

  • Anti-Bacterial Agents
  • beta-Lactams
  • fropenem