Large-scale, uniform DNA network on 11-mercaptoundecanoic acid modified gold (111) surface: atomic force microscopy study

Microsc Res Tech. 2007 Jul;70(7):572-7. doi: 10.1002/jemt.20436.

Abstract

Large-scale, uniform plasmid deoxyribonucleic acid (DNA) network has been successfully constructed on 11-mercaptoundecanoic acid modified gold (111) surface using a self-assembly technique. The effect of DNA concentration on the characteristics of the DNA network was investigated by atomic force microscopy. It was found that the size of meshes and the height of fibers in the DNA network could be controlled by varying the concentration of DNA with a constant time of assembly of 24 h.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / ultrastructure*
  • Fatty Acids
  • Gold
  • Microscopy, Atomic Force / methods*
  • Nanostructures
  • Nanotechnology
  • Plasmids / ultrastructure*
  • Sulfhydryl Compounds

Substances

  • 11-mercaptoundecanoic acid
  • Fatty Acids
  • Sulfhydryl Compounds
  • Gold
  • DNA