Renal complications associated with human parvovirus B19 infection in early childhood

Klin Padiatr. 2007 Mar-Apr;219(2):74-5. doi: 10.1055/s-2007-970071.

Abstract

A previously healthy two-year-old girl presented with proteinuria and macroscopic haematuria. Laboratory findings included haemolytic anaemia with thrombocytopenia. Interestingly, continuing reticulocytopenia was noted. Therefore an acute parvovirus B19 infection was suspected, which could be confirmed by serological and molecularbiological evidence. This case report underlines renal complications of parvovirus B19 infection in early childhood including haemolytic-uraemic syndrome (HUS)-like episodes, and potential pathogenetic mechanisms are discussed.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Diagnosis, Differential
  • Diuretics / administration & dosage
  • Female
  • Fluid Therapy
  • Furosemide / administration & dosage
  • Glomerulonephritis / diagnosis
  • Glomerulonephritis / therapy
  • Glomerulonephritis / virology*
  • Hematuria / virology
  • Hemolytic-Uremic Syndrome / diagnosis
  • Hemolytic-Uremic Syndrome / therapy
  • Hemolytic-Uremic Syndrome / virology*
  • Humans
  • Parvoviridae Infections / diagnosis
  • Parvoviridae Infections / therapy
  • Parvoviridae Infections / virology*
  • Parvovirus B19, Human / genetics
  • Parvovirus B19, Human / pathogenicity*
  • Polymerase Chain Reaction
  • Proteinuria / virology
  • Virulence

Substances

  • Diuretics
  • Furosemide