Fungal endophthalmitis complicating subconjunctival injection of triamcinolone acetonide in anterior scleritis

Ann Ophthalmol (Skokie). 2006 Fall;38(3):253-6. doi: 10.1007/s12009-006-0015-0.

Abstract

Fungal endophthalmitis following subconjunctival triamcinolone acetonide in anterior scleritis is a rare complication. Two patients with anterior scleritis, who received subconjunctival injection of triamcinolone developed fungal endophthalmitis. Both patients were positive by smear and polymerase chain reaction for 28S ribosomal RNA gene for fungus. Colletotrichum dematium was identified in one patient. Both patients responded well to pars plana vitrectomy and antifungal therapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / administration & dosage*
  • Anti-Inflammatory Agents / adverse effects*
  • Anti-Inflammatory Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Colletotrichum / isolation & purification
  • Conjunctiva
  • Endophthalmitis / diagnosis
  • Endophthalmitis / microbiology*
  • Endophthalmitis / surgery
  • Humans
  • Injections
  • Male
  • Microscopy, Acoustic
  • Middle Aged
  • Mycoses / chemically induced*
  • Mycoses / diagnosis
  • Mycoses / drug therapy
  • Mycoses / microbiology
  • RNA, Ribosomal, 28S / analysis
  • Scleritis / drug therapy*
  • Triamcinolone Acetonide / administration & dosage*
  • Triamcinolone Acetonide / adverse effects*
  • Triamcinolone Acetonide / therapeutic use
  • Vitrectomy

Substances

  • Anti-Inflammatory Agents
  • Antifungal Agents
  • RNA, Ribosomal, 28S
  • Triamcinolone Acetonide