The apolipoprotein A-I binding protein of placenta and the SP-40,40 protein of human blood are different proteins which both bind to apolipoprotein A-I

C Ehnholm; S E Bozas; H Tenkanen; L Kirszbaum; J Metso; B Murphy; I D Walker

doi:10.1016/0005-2760(91)90167-g

The apolipoprotein A-I binding protein of placenta and the SP-40,40 protein of human blood are different proteins which both bind to apolipoprotein A-I

Biochim Biophys Acta. 1991 Nov 27;1086(3):255-60. doi: 10.1016/0005-2760(91)90167-g.

Authors

C Ehnholm¹, S E Bozas, H Tenkanen, L Kirszbaum, J Metso, B Murphy, I D Walker

Affiliation

¹ National Public Health Institute, Helsinki, Finland.

PMID: 1742316
DOI: 10.1016/0005-2760(91)90167-g

Abstract

A complement-associated protein SP-40,40, which is a normal constituent of human blood, binds to the main apoprotein, apoA-I, of high density lipoprotein (HDL). This protein, which is identical to apolipoprotein J, was compared to another apoA-I binding protein purified from human placenta. Immunologically the two apoA-I binding proteins are different.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Antibodies, Monoclonal
Apolipoprotein A-I / metabolism*
Apolipoproteins / chemistry*
Apolipoproteins / immunology
Apolipoproteins / metabolism
Carrier Proteins / chemistry*
Carrier Proteins / immunology
Carrier Proteins / metabolism
Clusterin
Female
Glycoproteins*
Humans
Lipoproteins, HDL / chemistry*
Lipoproteins, HDL / immunology
Lipoproteins, HDL / metabolism
Molecular Chaperones*
Molecular Sequence Data
Placenta / chemistry*
Pregnancy
Sequence Homology, Nucleic Acid

Substances

Antibodies, Monoclonal
Apolipoprotein A-I
Apolipoproteins
CLU protein, human
Carrier Proteins
Clusterin
Glycoproteins
Lipoproteins, HDL
Molecular Chaperones