Mature Homogeneous Erythropoietin-Level Building Blocks by Chemical Synthesis: The EPO 114-166 Glycopeptide Domain, Presenting the O-Linked Glycophorin

Tetrahedron Lett. 2006 Nov 13;47(46):8013-8016. doi: 10.1016/j.tetlet.2006.09.045.

Authors

Jiehao Chen¹, Gong Chen, Bin Wu, Qian Wan, Zhongping Tan, Zihao Hua, Samuel J Danishefsky

Affiliation

¹ Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA.

Abstract

A synthesis of EPO 114-166 glycopeptide (1), presenting the O-linked glycophorin of erythropoietin, is described.

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