Abstract
The incorporation of multiple antigens into a single human papillomavirus (HPV) vaccine may induce immune interference. To evaluate whether interference occurs when HPV type 16 (HPV16) virus-like particles are combined in a multivalent vaccine, we conducted a study to evaluate anti-HPV16 responses among subjects receiving three-dose regimens of either a monovalent HPV16 vaccine or a quadrivalent HPV (types 6, 11, 16, and 18) vaccine.
Publication types
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Comparative Study
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Multicenter Study
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Randomized Controlled Trial
MeSH terms
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Adolescent
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Adult
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Antibodies, Viral / biosynthesis
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Antibody Formation / immunology*
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Double-Blind Method
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Female
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Human papillomavirus 16 / immunology*
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Humans
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Papillomavirus Infections / prevention & control*
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Papillomavirus Vaccines / administration & dosage
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Papillomavirus Vaccines / classification*
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Papillomavirus Vaccines / immunology*
Substances
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Antibodies, Viral
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Papillomavirus Vaccines