Late drug-eluting stent thrombosis and erythropoietin: cause and effect?

P A Gladding; M W Webster; P Kay

doi:10.1016/j.hlc.2007.01.002

Late drug-eluting stent thrombosis and erythropoietin: cause and effect?

Heart Lung Circ. 2007 Aug;16(4):305-7. doi: 10.1016/j.hlc.2007.01.002. Epub 2007 Apr 18.

Authors

P A Gladding¹, M W Webster, P Kay

Affiliation

¹ Auckland City Hospital, Greenlane Cardiovascular Service, Park Rd., Grafton, Auckland, New Zealand. [email protected]

PMID: 17446131
DOI: 10.1016/j.hlc.2007.01.002

Abstract

A case of late thrombosis of a sirolimus-eluting stent, 16 months after implantation, is described. Two weeks prior to presentation with stent thrombosis the patient had a 50% dose increase of longterm erythropoietin. The prothrombotic effect of erythropoietin may have precipitated the thrombotic event.

Publication types

Case Reports

MeSH terms

Adult
Angioplasty, Balloon, Coronary
Cardiovascular Agents / therapeutic use
Coated Materials, Biocompatible / therapeutic use*
Coronary Thrombosis / etiology*
Coronary Thrombosis / therapy
Dose-Response Relationship, Drug
Erythropoietin / adverse effects*
Humans
Male
Reoperation
Sirolimus / therapeutic use
Stents / adverse effects*

Substances

Cardiovascular Agents
Coated Materials, Biocompatible
Erythropoietin
Sirolimus