Choroidal folds in Vogt-Koyanagi-Harada disease

Am J Ophthalmol. 2007 May;143(5):900-901. doi: 10.1016/j.ajo.2006.11.050. Epub 2006 Dec 28.

Abstract

Purpose: To analyze choroidal folds in Vogt-Koyanagi-Harada (VKH) disease by fluorescein angiography (FA), indocyanine green angiography (ICGA), and optical coherence tomography (OCT).

Design: Retrospective, consecutive case series.

Methods: Records of 95 patients diagnosed with VKH disease from October 2001 to July 2006 were reviewed. All patients underwent FA, 17 patients underwent ICGA, and 20 underwent OCT.

Results: Of the 95 patients, 11 (12.0%) had choroidal folds and showed 10 to 15 hypofluorescent bands radiating from the optic disk that were similar to the large retinal vessels in shape and number on FA. On ICGA, the choroidal folds showed hyperfluorescence at the late stage. OCT showed clear folds but the number of folds was larger than on FA and ICGA.

Conclusions: Choroidal folds are not uncommon in VKH disease. FA, ICGA, and OCT can help to identify their pathogenesis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Choroid Diseases / diagnosis
  • Choroid Diseases / etiology*
  • Coloring Agents
  • Female
  • Fluorescein Angiography
  • Humans
  • Indocyanine Green
  • Male
  • Middle Aged
  • Retrospective Studies
  • Tomography, Optical Coherence
  • Uveomeningoencephalitic Syndrome / complications*

Substances

  • Coloring Agents
  • Indocyanine Green