Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors

ChemMedChem. 2007 Jul;2(7):987-91. doi: 10.1002/cmdc.200700023.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Acetylation
  • Cell Differentiation / drug effects
  • Cell Line, Tumor
  • Enzyme Inhibitors / chemical synthesis*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Granulocytes / cytology
  • Granulocytes / drug effects
  • Histone Methyltransferases
  • Histone-Lysine N-Methyltransferase / antagonists & inhibitors*
  • Humans
  • Methylation
  • Molecular Structure
  • Phosphorylation
  • Protein Methyltransferases

Substances

  • Enzyme Inhibitors
  • Histone Methyltransferases
  • Protein Methyltransferases
  • Histone-Lysine N-Methyltransferase