The goal of this study was to evaluate the thermoplasticity of conventional and thermoplastic gutta-percha and Resilon, a polyester polymer-based material. Specimens with standardised dimensions were made from the following materials: conventional and thermoplastic gutta-percha (Dentsply), conventional and thermoplastic gutta-percha (Endopoints) and Resilon. After 24 h, the specimens were placed in water at 70 degrees C for 60 s, and thereafter positioned between two glass slabs. Each set was compressed by a 5-kg weight. Digital images of the specimens before and after compression were obtained and analysed. The thermoplasticity of each material was confirmed by the difference between final and initial areas of each sample. The data were analysed statistically by anova and Tukey's test at a 5% significance level. Resilon had the highest thermoplasticity means (P < 0.05). Among the gutta-percha cones, Endopoints TP (thermoplastic) presented the highest thermoplasticity means and differed significantly from the other commercial brands (P < 0.05). Resilon had good thermoplasticity, endorsing its use as a thermoplastic root canal filling material.