[Pregnancy in a patient with Gitelman syndrome: a case report and review of literature]

J Gynecol Obstet Biol Reprod (Paris). 2007 May;36(3):310-3. doi: 10.1016/j.jgyn.2006.10.004. Epub 2006 Dec 27.
[Article in French]

Abstract

Gitelman syndrome (GS) is a tubulopathy characterized by hypokaliemia, hypomagnesiemia, metabolic alkalosis and hypocalciuria. We report a case of a 33-year-old pregnant woman with Gitelman Syndrome. Oral potassium chloride and magnesium citrate were prescribed and the course of the pregnancy was uneventful with vaginal delivery at term. The impact of GS on the physiologic adaptations to pregnancy is not well-known, with few reports to date. Monitoring of serum potassium and magnesium levels with supplementation, amniotic fluid and fetal growth is required to prevent obstetrical and fetal complications in a patient with GS.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Adult
  • Citric Acid / therapeutic use*
  • Female
  • Gitelman Syndrome / diagnosis
  • Gitelman Syndrome / drug therapy*
  • Humans
  • Organometallic Compounds / therapeutic use*
  • Potassium Chloride / therapeutic use*
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / drug therapy*
  • Pregnancy Outcome

Substances

  • Organometallic Compounds
  • Citric Acid
  • Potassium Chloride
  • magnesium citrate