Abstract
The genome of Stenotrophomonas maltophilia encodes a cell-cell signaling system that is highly related to the diffusible signal factor (DSF)-dependent system of the phytopathogen Xanthomonas campestris. Here we show that in S. maltophilia, DSF signaling controls factors contributing to the virulence and antibiotic resistance of this important nosocomial pathogen.
Publication types
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Research Support, Non-U.S. Gov't
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Retracted Publication
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Bacterial Proteins / genetics*
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Bacterial Proteins / metabolism
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Bacterial Proteins / physiology
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Cross Infection / microbiology
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Drug Resistance, Bacterial / genetics
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Gene Expression Regulation, Bacterial
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Genes, Bacterial
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Humans
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Metals, Heavy / pharmacology
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Multigene Family
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Mutation
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Signal Transduction / genetics*
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Signal Transduction / physiology
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Stenotrophomonas maltophilia / drug effects
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Stenotrophomonas maltophilia / genetics*
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Stenotrophomonas maltophilia / pathogenicity
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Virulence / genetics
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Xanthomonas campestris / genetics
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Metals, Heavy