Severe systemic adverse reaction to proton pump inhibitors in an infant

Pediatr Pulmonol. 2007 Jun;42(6):563-4. doi: 10.1002/ppul.20616.

Abstract

Episodes of respiratory distress with chest retraction and wheezing, sometimes associated with facial edema, were noted after administering the proton pump inhibitors omeprazole and esomeprazole in an infant with gastroesophageal reflux. The disturbances relieved dramatically after withdrawing the proton pump inhibitor.

Publication types

  • Case Reports

MeSH terms

  • Enzyme Inhibitors / adverse effects*
  • Esomeprazole
  • Female
  • Gastroesophageal Reflux / drug therapy
  • Gastroesophageal Reflux / surgery
  • Humans
  • Infant
  • Lung Diseases / chemically induced*
  • Lung Diseases / diagnosis
  • Omeprazole / adverse effects*
  • Proton Pump Inhibitors*
  • Respiratory Sounds / etiology

Substances

  • Enzyme Inhibitors
  • Proton Pump Inhibitors
  • Omeprazole
  • Esomeprazole