Abstract
Seven bla(IMP-1)-harboring Acinetobacter sp. isolates and one Pseudomonas putida clinical isolate were recovered from hospitalized patients. All isolates possessed a class 1 integron, named In86, carrying the same cassette array [bla(IMP1), aac(6')-31, and aadA1], which was plasmid located in five of the isolates. This report describes the ability of nonfermentative nosocomial pathogens to acquire and disseminate antimicrobial resistance determinants.
MeSH terms
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Acinetobacter / drug effects
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Acinetobacter / genetics
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Acinetobacter / isolation & purification
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Acinetobacter / pathogenicity
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Amino Acid Sequence
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Aminoglycosides / pharmacology*
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Anti-Bacterial Agents / pharmacology*
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Base Sequence
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Brazil / epidemiology
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Codon, Terminator
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Cross Infection
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Drug Resistance, Multiple, Bacterial / genetics*
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Gene Transfer, Horizontal
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Genes, Bacterial*
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Hospitals
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Humans
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Integrons / genetics*
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Open Reading Frames
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Plasmids / genetics
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Pseudomonas putida / drug effects
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Pseudomonas putida / genetics
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Pseudomonas putida / isolation & purification
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Pseudomonas putida / pathogenicity
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Transcription, Genetic
Substances
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Aminoglycosides
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Anti-Bacterial Agents
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Codon, Terminator
Associated data
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GENBANK/AJ640198
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GENBANK/AM283489
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GENBANK/AM283490