Hepatoid carcinoma of the ovary and management

Acta Obstet Gynecol Scand. 2007;86(4):498-9. doi: 10.1080/00016340600593117.

Abstract

The designation'hepatoid carcinoma' has been introduced as a unique type of carcinoma that arises outside the liver but resembles, to a considerable extent, hepatocellular carcinoma both histologically and immunohistochemically in its staining for alpha-fetoprotein (AFP). The minimum histological criteria of hepatoid carcinomas are the evidence of AFP production and abundant eosinophilic cytoplasm. These tumors have been reported in the ovary, the lung, the stomach, the renal pelvis, and the bladder. We, in this study, present a rare patient with primary hepatoid carcinoma of the ovary (OHC) and review the previous reports.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Neoplasms / secondary
  • Carcinoma, Hepatocellular / drug therapy
  • Carcinoma, Hepatocellular / pathology*
  • Carcinoma, Hepatocellular / secondary
  • Carcinoma, Hepatocellular / surgery
  • Diagnosis, Differential
  • Fatal Outcome
  • Female
  • Humans
  • Hysterectomy*
  • Immunohistochemistry
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / pathology*
  • Liver Neoplasms / surgery
  • Lung Neoplasms / secondary
  • Neoplasms, Multiple Primary
  • Ovarian Neoplasms / drug therapy
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery
  • Tomography, X-Ray Computed
  • alpha-Fetoproteins / biosynthesis*

Substances

  • alpha-Fetoproteins