The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system

Angew Chem Int Ed Engl. 2007;46(24):4474-6. doi: 10.1002/anie.200700268.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Enzyme Inhibitors / chemistry
  • Glycoside Hydrolases / antagonists & inhibitors*
  • Imino Sugars / chemistry
  • Imino Sugars / pharmacology*
  • Protein Binding
  • Static Electricity
  • Structure-Activity Relationship
  • Water

Substances

  • Enzyme Inhibitors
  • Imino Sugars
  • Water
  • Glycoside Hydrolases
  • endoglycoceramidase

Associated data

  • PDB/2OYK
  • PDB/2OYL
  • PDB/2OYM