[A case of maxillary sinus carcinoma showing long time survival after lung metastasis with administration of S-1 as tumor dormancy therapy]

Gan To Kagaku Ryoho. 2007 May;34(5):749-51.
[Article in Japanese]

Abstract

The patient is a 65-year-old man, who underwent curative resection for maxillary sinus carcinoma after chemoradiation. Lung metastases were observed two months following resection, and were treated with S-1 at a dose of 120 mg/day. One course of the S-1 administration regimen consisted of 2 weeks and a 1-week interval. The patient achieved long survival for 527 days with no adverse reaction. Therefore, this treatment on an outpatient basis greatly contributed to his quality of life. We consider S-1 as a first-line anti-cancer drug for tumor dormancy therapy.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Carcinoma, Squamous Cell / drug therapy*
  • Carcinoma, Squamous Cell / secondary
  • Carcinoma, Squamous Cell / surgery
  • Combined Modality Therapy
  • Drug Administration Schedule
  • Drug Combinations
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / secondary*
  • Male
  • Maxillary Sinus Neoplasms / drug therapy*
  • Maxillary Sinus Neoplasms / pathology
  • Maxillary Sinus Neoplasms / surgery
  • Oxonic Acid / therapeutic use*
  • Survivors
  • Tegafur / therapeutic use*

Substances

  • Antimetabolites, Antineoplastic
  • Drug Combinations
  • S 1 (combination)
  • Tegafur
  • Oxonic Acid