Abstract
Neonatal lupus has become an important model of passively acquired autoimmunity since the seminal observation in the late 1970s that sera from nearly all mothers of children with isolated congenital heart block (CHB) contain specific autoantibodies.
Publication types
-
Research Support, N.I.H., Extramural
-
Review
MeSH terms
-
Apoptosis / immunology
-
Dexamethasone / therapeutic use
-
Disease Progression
-
Fetal Heart / immunology
-
Glucocorticoids / therapeutic use
-
Heart Block / congenital*
-
Heart Block / immunology
-
Humans
-
Immunoglobulins, Intravenous / immunology
-
Infant, Newborn
-
Lupus Erythematosus, Systemic / diagnosis
-
Lupus Erythematosus, Systemic / immunology
-
Myocardium / immunology
-
Registries
-
Ribonucleoproteins / immunology
Substances
-
Glucocorticoids
-
Immunoglobulins, Intravenous
-
Ribonucleoproteins
-
SS-A antigen
-
Dexamethasone