Time courses of brain activation and their implications for function: a multichannel near-infrared spectroscopy study during finger tapping

Neurosci Res. 2007 Jul;58(3):297-304. doi: 10.1016/j.neures.2007.03.014. Epub 2007 Apr 7.

Abstract

The time courses of brain activation were monitored during a finger tapping task using multichannel near-infrared spectroscopy with a time resolution of 0.1s in 30 healthy volunteers. Task-induced brain activations were demonstrated as significant increases in oxygenated hemoglobin concentration ([oxy-Hb]) in a broad area around the motor cortex and significant decreases in deoxygenated hemoglobin concentration ([deoxy-Hb]) in a more restricted area, with a large degree of activation in the contralateral hemisphere. The time courses of the [oxy-Hb] changes varied depending on channel location: sustained activation across the task period in the motor cortex, transient activation during the initial segments of the task period in the somatosensory cortex, and accumulating activation along the task period in the frontal lobe. These characteristics are assumed to reflect the functional roles of the brain structures during the task period, that is, the execution, sensory monitoring, and maintenance of finger tapping.

MeSH terms

  • Adult
  • Brain Mapping
  • Cerebrovascular Circulation
  • Female
  • Fingers / innervation
  • Fingers / physiology*
  • Functional Laterality
  • Hemoglobins / metabolism
  • Humans
  • Male
  • Motor Cortex / metabolism*
  • Psychomotor Performance / physiology*
  • Reaction Time / physiology*
  • Spectroscopy, Near-Infrared*
  • Time Factors

Substances

  • Hemoglobins