Comparison of the extent of delayed-enhancement cardiac magnetic resonance imaging with and without phase-sensitive reconstruction at 3.0 T

Invest Radiol. 2007 Jun;42(6):372-6. doi: 10.1097/01.rli.0000263184.19773.aa.

Abstract

Objectives: To evaluate phase-sensitive reconstructed images versus magnitude images generated by an inversion recovery pulse sequence for the determination of myocardial infarct size in delayed-enhancement cardiac magnetic resonance (DE-CMR) at 3 T.

Materials and methods: Thirty patients were examined at 3 T and DE images were obtained 10 minutes after contrast agent administration using a phase-sensitive breath-hold segmented inversion recovery gradient echo sequence. From magnitude and phase images, the percentage of hyperenhanced myocardium was expressed. Contrast-to-noise ratio (CNR) measurements were performed in hyperenhanced and normal myocardium.

Results: We observed excellent correlation and concordance between hyperenhanced myocardium determined on phase-sensitive reconstructed and magnitude images. The mean CNR values were significantly higher in phase-sensitive reconstructed images compared with magnitude images (10.5 +/- 5.4 vs. 6.1 +/- 4.8; P < 0.001).

Conclusions: DE-CMR with phase-sensitive reconstruction at 3.0 T provides similar results to magnitude images, but with a significantly greater CNR between infarcted and normal myocardium.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cardiomyopathy, Dilated / pathology*
  • Contrast Media
  • Female
  • Gadolinium DTPA
  • Humans
  • Image Processing, Computer-Assisted*
  • Linear Models
  • Magnetic Resonance Imaging, Cine / methods*
  • Male
  • Middle Aged
  • Myocardial Infarction / pathology*

Substances

  • Contrast Media
  • Gadolinium DTPA