[Complications after sentinel lymph node excision in patients with malignant melanoma]

Ann Dermatol Venereol. 2007 May;134(5 Pt 1):439-42. doi: 10.1016/s0151-9638(07)89210-6.
[Article in French]

Abstract

Introduction: Side-effects occurring after sentinel lymph node excision in malignant melanoma patients have been poorly evaluated to date. The aim of the present study was to assess the side-effects of sentinel lymph node excision in this population.

Patients and methods: All consecutive malignant melanoma patients undergoing sentinel lymph node excision between March 2000 and December 2002 were included in this retrospective study. Patients with a metastatic sentinel node subsequently undergoing lymph node dissection were excluded. Median follow-up of patients was 12.6 +/- 8.8 months. Complications were classified as "early" (i.e. occurring the month following surgery), or "late" (after this time).

Results: Forty malignant melanoma patients (17 males, 23 females) with a normal histologic examination of their sentinel lymph node were included. They belonged to a series of sixty-one melanoma patients undergoing lymph node excision. Fourteen complications were observed in ten patients. Two early complications were seen: hematoma (n=1) and deep venous thrombosis with pulmonary embolism (n=1). Twelve late complications were observed: mild lymphoedema (n=5), hypertrophic scars (n=2), painful scars (n=4), and one chronic seroma (n=1). Many complications (33%) were observed after excision in the inguinal area.

Discussion: The complications of sentinel lymph node excision must be considered in determining the benefit/risk ratio of this technique.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Lymph Node Excision / adverse effects*
  • Lymph Nodes / diagnostic imaging
  • Male
  • Melanoma / diagnostic imaging
  • Melanoma / pathology
  • Melanoma / surgery*
  • Middle Aged
  • Radiography
  • Radiopharmaceuticals
  • Retrospective Studies
  • Sentinel Lymph Node Biopsy*
  • Skin Neoplasms / diagnostic imaging
  • Skin Neoplasms / pathology
  • Skin Neoplasms / surgery*
  • Technetium Tc 99m Sulfur Colloid

Substances

  • Radiopharmaceuticals
  • nanocis
  • Technetium Tc 99m Sulfur Colloid