Abstract
The macrocyclic host cucurbit[7]uril exhibits highly specific inhibitory effects on the activity of proteases, which can be analyzed by a host-substrate complexation model.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bridged-Ring Compounds / chemistry*
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Bridged-Ring Compounds / pharmacology*
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Imidazoles / chemistry*
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Imidazoles / pharmacology*
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Kinetics
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Molecular Structure
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Peptide Hydrolases / chemistry*
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Protease Inhibitors / chemistry*
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Protease Inhibitors / pharmacology*
Substances
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Bridged-Ring Compounds
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Imidazoles
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Protease Inhibitors
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cucurbit(7)uril
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Peptide Hydrolases