Abstract
We have investigated two pedigrees in an attempt to detect the putative linkages between affective disorder and c-Ha-ras-1 oncogene and the insulin gene on chromosome 11, or hypoxanthine phosphoribosyltransferase (HPRT) on X chromosome. The linkage between affective disorders and the markers on chromosomes 11 and X was ruled out with the assumption of no recombination.
MeSH terms
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Bipolar Disorder / genetics*
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Bipolar Disorder / psychology
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Chromosomes, Human, Pair 11*
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Depressive Disorder / genetics*
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Depressive Disorder / psychology
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Genetic Linkage / genetics*
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Genetic Markers / genetics*
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Haplotypes / genetics
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Humans
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Pedigree
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Polymorphism, Genetic / genetics
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Psychotic Disorders / genetics*
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Psychotic Disorders / psychology
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Sex Chromosome Aberrations / genetics*
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X Chromosome*