Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting

Clin Vaccine Immunol. 2007 Jul;14(7):924-5. doi: 10.1128/CVI.00025-07. Epub 2007 May 30.

Abstract

1,3-Beta-D-Glucan serum levels have demonstrated good diagnostic sensitivity and specificity for the diagnosis of candidiasis in adult patients, but normal levels for children have not been established. We found higher 1,3-beta-D-glucan levels in children than those previously reported in adults.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Age Factors
  • Biomarkers / blood*
  • Candidiasis / blood*
  • Candidiasis / diagnosis*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Male
  • Microbiological Techniques
  • Sensitivity and Specificity
  • beta-Glucans / blood*

Substances

  • Biomarkers
  • beta-Glucans
  • beta-1,3-glucan