[Salivary involvement in IgG4-related multifocal fibrosclerosing disease]

Ann Otolaryngol Chir Cervicofac. 2007 Jul;124(3):131-5. doi: 10.1016/j.aorl.2007.01.004.
[Article in French]

Abstract

Objectives: To report a case of IgG4-related multifocal fibrosclerosis, revealed by a multifocal salivary involvement.

Material and methods: A 59-year-old man, with chronic pancreatitis, was managed for fibrotic involvement of the 2 submaxillary glands and the 2 parotids. Clinical, radiological, and histologic features were retrospectively studied.

Results: Pathological features of submandibular gland revealed a chronic sclerosing sialadenitis. Retroperitoneal fibrosis in computed tomography and high rate of IgG4 are objectived. The diagnosis of IgG4-related multifocal fibrosclerosis is evoked. The patient's state improved with corticosteroid therapy.

Conclusion: Salivary involvement in IgG4-related multifocal fibrosclerosis must be recognized in salivary medical pathology.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Humans
  • Immunoglobulin G / immunology*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Pancreas / diagnostic imaging
  • Pancreas / pathology
  • Pancreatitis, Acute Necrotizing / complications*
  • Pancreatitis, Acute Necrotizing / diagnosis
  • Pancreatitis, Acute Necrotizing / drug therapy
  • Salivary Glands / immunology
  • Salivary Glands / pathology
  • Sialadenitis / diagnosis*
  • Sialadenitis / drug therapy
  • Sialadenitis / immunology*
  • Tomography, X-Ray Computed

Substances

  • Anti-Inflammatory Agents
  • Immunoglobulin G