Abstract
Recent quantitative analyses of ribosomal protein trafficking in HeLa cells have revealed a prominent and unexpected role for the proteasome in regulating the availability of ribosomal proteins for subunit assembly.
MeSH terms
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Cell Nucleolus / metabolism
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Fluorescence Recovery After Photobleaching
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Green Fluorescent Proteins / analysis
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HeLa Cells
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Humans
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Isotope Labeling
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Proteasome Endopeptidase Complex / physiology
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Protein Transport
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Proteomics
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Recombinant Fusion Proteins / analysis
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Ribosomal Proteins / metabolism*
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Ribosomes / metabolism*
Substances
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Recombinant Fusion Proteins
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Ribosomal Proteins
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Green Fluorescent Proteins
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Proteasome Endopeptidase Complex