Abstract
Selected 5-ethynyl derivatives of 2'-deoxyuridine are shown to fluorometrically respond to hybridization and selectively base-pair to adenine whilst maintaining duplex stability.
MeSH terms
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Adenine / chemistry
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Alkynes / chemistry*
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Base Pairing
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DNA / chemistry*
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Deoxyuridine* / analogs & derivatives
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Deoxyuridine* / chemical synthesis
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Deoxyuridine* / chemistry
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Fluorescence
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Fluorescent Dyes* / chemical synthesis
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Fluorescent Dyes* / chemistry
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Hot Temperature
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Nucleic Acid Denaturation
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Nucleic Acid Hybridization*
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Oligonucleotides* / chemical synthesis
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Oligonucleotides* / chemistry
Substances
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Alkynes
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Fluorescent Dyes
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Oligonucleotides
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DNA
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Adenine
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Deoxyuridine