Direct quantitative tomographic reconstruction for weakly absorbing homogeneous phase objects

Rev Sci Instrum. 2007 May;78(5):053701. doi: 10.1063/1.2735583.

Abstract

We examine a direct filtered back projection approach that is suitable for the reconstruction of weakly absorbing homogeneous phase objects. Like recent similar approaches this method needs only one intensity image in each projection without the requirement for an intermediate step of phase retrieval. We tested the method using simulation and experimental results. Simulation results show good quantitative reconstruction which includes the correct refractive index value and distribution of the sample. However, experimental result still indicates the presence of artifacts.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms*
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, Optical / methods*