Abstract
Analysing 101 cases of nosocomial meningitis due to staphylococci other than S. aureus within last 15 years, coagulase negative staphylococci represented the commonest pathogen. Major risk factor for staphylococcal meningitis was prior neurosurgery, mainly ventriculoperitoneal shunt insertion. Ten of 101 cases were caused by glycopeptide intermediate resistant strains in patients pretreated with multiple combination of antibiotics including vancomycin and shunt exchanges: 76% of strains were also oxacillin resistant.
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Child
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Child, Preschool
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Cross Infection / drug therapy
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Cross Infection / etiology
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Cross Infection / microbiology*
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Humans
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Infant
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Infant, Newborn
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Meningitis, Bacterial / drug therapy
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Meningitis, Bacterial / etiology
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Meningitis, Bacterial / microbiology*
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Neurosurgical Procedures / adverse effects
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Postoperative Complications / drug therapy
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Postoperative Complications / microbiology*
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Retrospective Studies
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Staphylococcaceae / isolation & purification
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Staphylococcal Infections / complications*
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Staphylococcal Infections / drug therapy
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Ventriculoperitoneal Shunt / adverse effects