Cytogenetics of six follicular thyroid adenomas including a case report of an oxyphil variant with t(8;14)(q13;q24.1)

Cancer Genet Cytogenet. 1991 Oct 15;56(2):231-5. doi: 10.1016/0165-4608(91)90175-t.

Abstract

Cytogenetic analyses were performed on six follicular thyroid adenomas. Five had normal karyotypes and one, an oxyphil adenoma, had a t(8;14)(q13;q24.1). This patient also had a history of pleomorphic adenoma of the parotid gland. This clonal abnormality may suggest a primary genetic lesion in this patient who had two different benign neoplasms.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / genetics*
  • Aged
  • Chromosomes, Human, Pair 14*
  • Chromosomes, Human, Pair 8*
  • Female
  • Humans
  • Neoplasms, Second Primary / genetics
  • Parotid Neoplasms / genetics
  • Thyroid Neoplasms / genetics*
  • Translocation, Genetic*